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Rheumatology

Metotab®

Product Description

Metotab® is an oral methotrexate product as a tablet. It is taken once weekly and is used in the treatment of various autoimmune diseases.

Active Ingredient

Methotrexat (MTX)

Mode of Action

Methotrexate is a folic acid antagonist which belongs to the class of cytotoxic agents. It acts by the competitive inhibition of the enzyme dihydrofolate reductase and thus inhibits DNA synthesis. Methotrexate is a very well-known so-called disease modifying antirheumatic drug (DMARD) meaning that it does not just relieve the pain of patients with joint inflammation and/or psoriasis, but actually helps to stop and prevent this inflammation and the resulting damage.

Administration

Oral

Indication

  • Severe, active rheumatoid arthritis in adult patients
  • Severe and generalised psoriasis vulgaris, especially of the plaque type, in adult patients who do not respond to conventional therapy.

Dosage

Tablet: 

  • 2.5 mg
  • 7.5 mg
  • 10 mg

Not all pack sizes may be marketed.

Materials

Abbreviated product information

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